SBIR/STTR Research Award
Monitoring Cell Viability Through NADH Fluorescence
Award amount
$49,996Program and phase
SBIR · Phase IAward year
1993Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- Not reported
- Recipient company
- Laser Science, Inc.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- Not reported
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
We will develop a laser-based instrument to monitor cell viability through NADH fluorescence when the tissue is illuminated with a pulsed nitrogen laser. Key experiments have already been performed on isolated, perfused rat liver which indicate the feasibility of this approach. The research will be continued in order to determine the optimum operation parameters for the instrument. In addition, a complete instrument design will be made. Phase II will be devoted to further experiments and to construction and initial testing of a prototype instrument.
Technology keywords
Not reported