On-Chip Metrology for Total Chemical Analysis

A multi-manifold flow system integrated on a Chip, with valve-less switching of solvent flow between channels and electro-osmotic pumping of an aqueous solvent, if successfully developed has the potential of fundamentally changing the way chemical analysis is done. For this technology to become a practical reality, it is mandatory that fully integrated microsystems be developed. A critical component of such an integrated microsystem would be a micro-detector with the ability to rapidly, reliably, and productively meter chemical composition in micromolar concentrations eluted through the microchannels on a TAS chip. Nanomaterials Research Corporation (NRC) seeks to demonstrate such a microsensor. Phase I will establish the proof-of-concept. Phase II will optimize, integrate and implement prototype on-chip chemical analysis system. Phase III will commercialize the technology.