SBIR/STTR Research Award
Discovering Novel Antipseudomonal Agents
Award amount
$249,965Program and phase
SBIR · Phase IAward year
2021Award details
- Awarding agency
- Department of Defense
- Branch
- Defense Health Agency
- Recipient company
- CFD Research Corporation
- Proposal award date
- 2021-07-26
- Contract end date
- 2022-02-25
- UEI
- V3KCP1HNFM33
- Solicitation number
- 21.1
- Topic code
- DHA211-008
Research abstract
We have identified a novel protein target which is specific to Pseudomonas aeruginosa (PA). Inhibition of this target will decrease PA virulence, restore the host immune response, and balance the microbiome in addition to inhibiting PA growth. In this project we will conduct a high throughput screening campaign to discover inhibitors of the target protein. Then we will assess in vitro potency and toxicity to select a top hit compound for in vivo studies during the Phase II.
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- Multiphysics Modeling Framework for Raindrop-Induced Material Damage
- Ground Technologies for Surface Operation Risk Mitigation
- Supportive Tactical Aide Foresight Framework (STAFF)
- Soil Cohesion Effects on Cratering and Transport of Regolith due to Plume-Surface Interaction
- Modular and Scalable Machine Learning Framework for Infrared Search and Track
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- Novel Antibiotics Targeting Multidrug-Resistant Pseudomonas Aeruginosa Infections
- Novel Antibiotic Targeting Multidrug-Resistant Pseudomonas Aeruginosa Infections
Research funding history
947 SBIR/STTR records share this UEI (1987–2026). Reported award amounts total $350,893,199. Reported amounts are not federal obligations.
Phases: Phase I, Phase II, Phase II – Direct to Phase II
Agencies: Department of Defense, National Aeronautics and Space Administration, Department of Health and Human Services, National Science Foundation, Department of Commerce, Department of Energy