SBIR/STTR Research Award

ADVANCED NEXT GEENRATION RADIO FREQUENCY COILS FOR MAGNETIC RESONANCE IMAGING

Award identifier e1d08f9d410bb2af6c1088b5ef609d44dbd8cc771773bc8b12f9c35387760ca7Awarding agency Department of Health and Human Services · National Institutes of Health

Award amount

$2,256,312

Program and phase

SBIR · Phase II

Award year

2021

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Award details

Awarding agency
Department of Health and Human Services
Branch
National Institutes of Health
Recipient company
ADVANCED IMAGING RESEARCH, INC.
Proposal award date
2021-05-10
Contract end date
2025-04-30
UEI
MWJ5LUKXD3B7
Solicitation number
PA18-871
Topic code
101

Research abstract

Magnetic resonance imaging (MRI) is a safe, non-ionizing diagnostic tool. The overall goal of this project is to arrive very close to the ultimate intrinsic signal to noise ratio (UISNR) for a given MRI magnet field strength by combining innovations in very advanced transceiver technology. In Phase I, a high performance head RF coil receiver array will be prototyped and SNR performance compared to an existing commercial product. Emphasis in Phase II will be towards Phase I coil optimization, mechanical housing design followed by systematic phantom validation. MRI is the preferred method for examining soft tissue structures. However MRI signals are weak due to the small difference in energy levels population of parallel and anti-parallel spins (~6ppm at 1.5T) that contribute to the signal. Clinical MRI exams demand high resolution and/or fast scanning. Since SNR is the main limitation on fulfilling these requirements, it is the most important parameter of MRI systems. MRI SNR can be increased by signal averaging at the expense of lengthy scan times. Pursuit of higher SNR on one hand has resulted in a shift toward the use of higher static magnetic fields which is expensive and has siting and safety issues. On the other hand, we are rapidly approaching limitations in MRI systems with greater number of receiver channels. We propose novel innovations to optimize MRI SNR for a given magnet field strength. Generally SNR can be increased by increasing the signal strength or by reducing noise. We propose novel combinations to achieve maximum, near ultimate intrinsic MRI SNR by efficiently accomplishing both. The technology proposed has broad applications within and outside of MRI. A successful project will improve the MR image quality in shorter scan times thereby alleviating burden on high cost, high magnet field based MRI systems. The work proposed is original.

Technology keywords

Not reported

Other awards by this recipient

Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.

Awards with the same topic code

Verified by an exact topic code match. This is not a text-similarity match.

Research funding history

18 SBIR/STTR records share this UEI (1997–2024). Reported award amounts total $13,539,176. Reported amounts are not federal obligations.

Phases: Phase I, Phase II

Agencies: Department of Health and Human Services, National Aeronautics and Space Administration

Agency intelligence

Department of Health and Human Services

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