StampPump:Proof of Principle for a Disruptive Insulin Delivery Technology

StampPump will be a pre filled disposablepostage stamp sizedxx mmfully closed loop insulin pump that will carry enough ultra rapid Uinsulin to manage blood glucose for a full weekOur goal is to disrupt the insulin therapy market with a low cost system that delivers significantly better adherence and outcomes for Typeand Typediabetics who need chronic insulin supplementationThis grant will enable proof of principle for the StampPump s fluidics and control systemsThe specific aims are to refine and prototype designs ofreservoirpumping mechanismandsubcutaneous cannula insulin delivery system andto create a working breadboard prototype of fluidics and associated control electronics that meets bench testing benchmarksBecause StampPump is critically enabled by Thermalin s ultra rapid actingroom temperature stableUformulation of a novel insulin analogdemonstrating the system s compatibility with insulin is a sub aimA follow on Phase II application would enable a large animal prototype and proof of concept StampPumpa pre filled disposablepostage stamp sizedxx mmfully closed loop insulin pump that will carry sufficient ultra rapid Uinsulin to manage blood glucose for a full week for andgtof TypeDiabetes patientswould be a disruptivei elower cost with more featuresoption that would dramatically lower the burden of insulin therapyincrease adherenceand improve outcomes andampquality of lifeThis project will reduce risk of the project by delivering proof of principle for the required miniature fluidics and control systems