SBIR/STTR Research Award
Enhanced Rapid Assay for Monitoring Immunosuppressant Drugs in Plasma
Award amount
$149,925Program and phase
SBIR · Phase IAward year
2019Award details
- Awarding agency
- Department of Defense
- Branch
- Army
- Recipient company
- INTELLIGENT OPTICAL SYSTEMS, INC.
- Proposal award date
- 2019-02-06
- Contract end date
- 2020-06-23
- UEI
- NLDHG92SMX37
- Solicitation number
- 18.3
- Topic code
- A18-145
Research abstract
Frequent monitoring of immunosuppressant drugs in vascularized composite allotransplantation (VCA) is necessary to avoid transplant rejection and drug toxicity. This is mainly attributed to the short therapeutic window and the differences in pharmacokinetics and pharmacodynamics between individuals. Intelligent Optical Systems, Inc. (IOS) proposes to adapt its advanced rapid assay technology so as to use a simple finger stick assay to detect tacrolimus (FK506) and cyclosporine in whole blood. The proposed approach benefits from the advances in current rapid assay technology IOS has developed and validated in a number of clinical settings, leading us to expect a TRL of 6 or above at the end of Phase II.
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- Laser Ultrasonic Testing for In-Space Welding Environments
- Reliable, Low-cost, and Compact Real-time Ammonia Monitor for Enclosed Livestock Facilities
- In-situ, Robust, Low Size, Weight, and Power Trace-gas Detector
- Advanced Laser Ultrasonic Sensor for Fuel Rod Characterization
- In-Reactor Laser Ultrasonic Sensor for Fuel Rod Pressure and Fission Gas
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- Enhanced Rapid Assay for Monitoring Immunosuppressant Drugs in Whole Blood
- At-Home Minimally Invasive Tacrolimus Plasma Level Monitoring Device
- Immunosuppressant Drug Monitor
- Enhanced Rapid Assay for Monitoring Immunosuppressant Drugs in Plasma
- Rapid At-home Test for Monitoring Tacrolimus Levels in Blood
Research funding history
264 SBIR/STTR records share this UEI (1998–2025). Reported award amounts total $77,140,779. Reported amounts are not federal obligations.
Phases: Phase I, Phase II
Agencies: Department of Defense, Department of Health and Human Services, National Aeronautics and Space Administration, Department of Energy, Environmental Protection Agency, Department of Agriculture