Low-Profile Wearable Drug Delivery System for Medical Countermeasures

All US Armed Forces personnel are trained on using auto-injectors (AIs) such as the ATNAA (Antidote Treatment – Nerve Agent Auto-Injector) and CANA (Convulsant Antidote for Nerve Agent) for use against nerve agent poisoning. Although effective, these AIs have many shortcomings, including risk of nerve and bone damage, accidental injection, and are not designed to provide rapid sequential doses or a programmed long-term dose. There is a strong unmet need for an on-body automated delivery device coupled to on-body sensors with remote activation that is capable of dosing-on-demand of multiple MCs for both traditional and novel threats. Clear Scientific proposes to develop a wearable drug-delivery system to meet the requirements of the modern warfighter. The prototype wearable will be capable of on-demand delivery of antidotes. The system will be small enough that several units could be placed on the body simultaneously. On board electronics will enable integration with on-body sensors and wireless systems.