Non-Invasive Venous Waveform Analysis (NIVA) in patients with Heart Failure (HF)

Volume overloadcongestionoccurs in patients with heart failureHFand is the leading cause of hospitalization in the elderly worldwideUnfortunatelyclinical signs and symptomslaboratory valuesand existing diagnostic tools are unreliable in providing accurate assessment of volume statusUsing a unique physiologic signalNon Invasive Venous waveform AnalysisNIVAVoluMetrix has developed a proprietary deviceVasaWatchand algorithm designed for monitoring volume status in HF patientsProof of concept data in humans and experimental animal modelsdemonstrate that VasaWatch provides a reliable indication of intravascular volume statusThe studies in this Fast Track SBIR will establish that VasaWatch is a safesensitiveinexpensive method for non invasive volume status monitoring in patients with HF Decompensated HF is the leading cause of hospitalizationHF leads to water accumulation in the tissueslungs and legsresulting in shortness of breath and leg swellingThis project will advance the development an accurateinexpensiveeasy to use deviceVasaWatchfor volume measurements in patients with HFUse of these devices will ultimately help health care providers and patients prevent water overloadThe long term goal is to prevent costly hospital readmissionsimprove quality of liveand reduce mortality in patients with HF