SBIR/STTR Research Award

Deep Learning for Automated Aortic Stenosis and Valvular Heart Disease Detection Using a Digital Stethoscope

Award identifier e70c3c727a20a200f012a8ce8f5579fab329c64b17a7efe45264c24c84a4b220Awarding agency Department of Health and Human Services · National Institutes of Health

Award amount

$295,881

Program and phase

SBIR · Phase I

Award year

2018

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Award details

Awarding agency
Department of Health and Human Services
Branch
National Institutes of Health
Recipient company
EKO Devices, Inc.
Proposal award date
2018-07-01
Contract end date
2019-12-31
UEI
GM3UL6PBJKD3
Solicitation number
PA17-302
Topic code
NHLBI

Research abstract

ProjectSummary Abstract ThisSBIRPhaseIprojectwilldevelopadeeplearning basedclinicaldecisionsupportalgorithm foridentifyingaorticstenosisfromheartsoundsrecordedusingtheEkoCoreDigital StethoscopeThisscreeningtoolwillhelptodecreasethenumberofpatientswithsevere asymptomaticaorticstenosisthatremainundertreatedsimplybecausetheconditionisnot diagnosedAuscultationiscommonlythemethodbywhichvalvularheartdiseaseisfirst detectedbutcasesoftenfailtobereferredtoechocardiographyfordiagnosisbecause cliniciansfailtodetectheartmurmursparticularlyinnoisyorrushedenvironmentsToaddress thischallengeEkohaddevelopedtheCoreadigitalstethoscopeattachmentthatcanbeadded in linetoaclinician sexistingstethoscopethatamplifiesheartsoundsandstreamsdigitized phonocardiogramstoasmartphonetabletorpersonalcomputerTherethesignalcanbe analyzedwiththedecisionsupportalgorithmwewilldevelopaspartofthisprojectThespecific aimsofthisstudyaretocollectadatabasewithcondition specificrecordinglabelsto enabledeeplearningforheartsoundsthoughclinicaldatacollectionatUCSFandto developandevaluateadeepconvolutionalneuralnetwork basedalgorithmtrainedonthe databaseByintegratingthisdeeplearningalgorithmintoEko smobileandcloudsoftware platformcurrentlyusedbycliniciansatoverinstitutionsworldwideweanticipatethis algorithmwillenablemoreaccuratescreeningforaorticstenosisleadingtoearlierdiagnosis andbetterpatientoutcomes SBIRProjectNarrative Valvularheartdiseaseandaorticstenosisinparticulararebecomingincreasinglyprevalent manifestationsofpoorcardiovascularhealthinboththedevelopedanddevelopingworldA highly accurateclinicaldecisionsupportalgorithmthatisabletodetectaorticstenosiswill impactpublichealthbyreducingunnecessaryreferralsforechocardiographyandpromoting earlyandaccuratediagnosisinunderservedareaswithlimitedaccesstosubspecialtycare

Technology keywords

Not reported

Other awards by this recipient

Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.

Awards with the same topic code

Verified by an exact topic code match. This is not a text-similarity match.

Research funding history

4 SBIR/STTR records share this UEI (2018–2022). Reported award amounts total $6,376,175. Reported amounts are not federal obligations.

Phases: Phase II, Phase I

Agencies: Department of Health and Human Services

Agency intelligence

Department of Health and Human Services

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