A Novel Nasogastric Feeding Tube for Optimizing Nutritional Administration in Older Adults

Abstract Nasogastric enteral feeding is a non invasive life saving therapy for older adults who are unable to eat or swallow due to functional decline or age related medical conditions such as stroke Every year nursing facility and home care residents and of stroke patients in the United States receive enteral feedings Nasogastric NG tubes are widely used but pose a serious threat when erroneously inserted or dislodged e g through tube curling into organs other than the stomach Several approaches are currently used for placement detection however these methods are limited by either their proven unreliability high costs and or risks Even when NG tubes are safely positioned an optimal amount of nutrition must be delivered at the right time for patients to thrive However tube fed patients are subject to over under and delayed feedings with particularly acute complications in frail older adults The most common nursing intervention to determine feeding rates is to periodically aspirate the gastric contents with a syringe and measure the total food and gastric fluid volume also known as the gastric residual volume GRV However this method is cumbersome and highly affected by user time and patient dependent factors The residual food volume RFV has been found to be an alternative metric of gastric function also known as gastric emptying However RFV detection methods are restricted in their use as well For many patients the risks and costs associated with the current GRV or RFV measurements outweigh the benefits As such there is an urgent need for an improved enteral feeding system that reduces risk optimizes feeding and can be implemented in any medical care facility TheraNova LLC has developed a smart NG enteral feeding system dubbed Gravitas which can automatically identify the device position between various tissues in real time assisting placement and alerting for tube dislodgment and assess gastric and food volumes in real time enabling delivery of the right amount of food at the right time The Gravitas prototype has demonstrated early feasibility through studies in healthy porcine and human subjects The main goal of this project is to validate the Gravitas device on the bench and in vivo and compare the device measurements with the current gold standards After identifying the optimal electrode configuration of the device on the bench we will verify the ability of the device to differentiate between the stomach and other tissues and accurately detect GRV and RFV in pigs This research will ultimately allow caregivers to confidently insert the Gravitas feeding tube act fast when the tube is directed in the wrong tissue and detect the gastric function to optimize food delivery in older adults Narrative Nasogastric enteral feeding is a non invasive life saving therapy for older adults who are unable to eat or swallow due to functional decline or age related medical conditions such as stroke Current nasogastric tubes suffer from potentially fatal misplacements and suboptimal delivery of nutrition This Phase I SBIR project proposes the development of a novel enteral feeding system that reduces risk optimizes feeding and can be implemented in any medical care facility