Dual Mode Hand Held Intraoperative Imager

Radionuclide guided intraoperative probes increase the specificity of tissue biopsiesenable minimalaccess incisionsreduce inpatient hospital utilizationand contribute to improved patient recoveryAt presentmost such probes on the market are non imagingand provide no ancillary information of surveyed areassuch as clear delineations of malignant tissuesOur goal is to develop a revolutionary new imaging probethe Imaging Beta ProbeIBPintended for rapid localization of lesions by sensing gamma raysfollowed by real time high sensitivity imaging of short range beta particles or positronsThis ergonomically designed probe will be small and easy to use during surgeryand is made possible by the recent development of solid state photomultipliers and hybrid scintillation technologies at RMDThe probe will provide continuous real time audio and or video feedback of emissions from surveyed areas to the surgeon for rapid and accurate delineation and precise excision of lesionswith minimal sacrifice of surrounding healthy tissueAfter excision of suspect tissuethe IBPwill allow the surgeon to check the tumor bed and margins for any remaining cancerous and precancerous tissuefine tumors or other tissuese gendometrialcapable of uptake of the administered tracerthat are otherwise obscured by background radiationOur motivation in pursuing the proposed Imaging Beta Probe design is that it will provide the first radical change in probe technology in decades andmost importantlysignificant improvement in and broadening of the clinical capabilities of intraoperative and external diagnostic probesDevelopment of this technology will provide an imaging tool for surgeons to detect PET positive lesions intra operativelywhich will advance their ability to confirm data provided by PET scans with biopsy materialFurthermorethese tools may allow a surgeon to perform a PET guided exploration and therapeutic excision of a small lesion that would otherwise be undiscovered by conventional exploration or treated by a harsh empiric regimen of chemotherapy or radiation Radionuclide guided intraoperative probes increase the specificity of tissue biopsiesenable minimalaccess incisionsreduce inpatient hospital utilizationand contribute to improved patient recoveryOur goal is to develop a revolutionary new imaging probethe Imaging Beta ProbeIBPintended for rapid localization of lesions by sensing gamma raysfollowed by real time high sensitivityhigh resolutionimaging of short range beta particles or positronsDevelopment of this technology provides an imaging tool for surgeons to detect and delineate PET positive lesions intraoperativelywhich will advance their ability to confirm data provided by PET scans with biopsy material