Size Resolved Measurement of Ultrafine and Nanometer Particle Concentrations

DESCRIPTION provided by applicant Proposed is a miniature sensor for real time measurement of nano particle size concentration surface area and lung deposition metrics This instrument combines two novel technologies a self sustaining laminar flow water condensation particle counter and collector developed by our firm and the opposed migration aerosol classifier developed at the California Institute of Technology The self sustaining water condensation counter provides single particle detection does not require liquid fill reservoirs and can be operated in any orientation The opposed migration aerosol classifier provides particle size selection based on electrical mobility in an inherently compact form Both technologies are compatible with devices small enough to be wearable The instrument is configured to cover the particle size range from nm to nm when configured as a personal sampler and can extend to near um when configured as a hand held device Reported parameters are nano particle number distribution total number concentration geometric mean diameter and region specific respiratory deposition potential In Phase I research we demonstrated the precision and accuracy of our technology In Phase II we will design construct and test an integrated system that we will be unobtrusive battery operable and suitable for personal monitoring This instrument will provide a means to monitor on a routine basis human exposures associated with airborne synthesized nano materials PUBLIC HEALTH RELEVANCE Through development and validation of a compact wearable sensor this research will provide a critical tool for assessing human exposure and inhaled does to ultrafine and nanometer sized airborne particles It will aid in assessing occupational and community exposures to nanoparticles generated from combustion sources or those produced in either the fabrication or use of nano engineered materials