SBIR/STTR Research Award

Development of a cross-serotype Adenovirus vaccine

Award identifier 764bf04a7c19b72fabb6679bb69c45225ca70a031f5d24614b1e2cc38a7d0887Awarding agency Department of Defense

Award amount

$99,798

Program and phase

SBIR · Phase I

Award year

2015

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Award details

Awarding agency
Department of Defense
Branch
Not reported
Recipient company
BIOLOGICAL MIMETICS, INC.
Proposal award date
2015-09-29
Contract end date
2016-04-28
UEI
LJARDLY9MMK5
Solicitation number
2015.1
Topic code
A15-051

Research abstract

We propose to develop a single antigen that stimulates cross-protective immunity against Ad4 and Ad7 serotypes as a method of reducing the costs associated with manufacturing the vaccine. By using our proprietary Immune Refocusing Technology (IRT), we will design and engineer a panel of recombinant IRT adenoviruses that each contain mutated codons at one epitope. Sera from mice immunized with the antigens will be tested for neutralization of Ad4 and Ad7, as well as Ad 3, 14, and 21. 2nd-generation IRT antigens containing multiple combinations of antigens identified in the leading antigens will be examined in a future study.

Technology keywords

Not reported

Other awards by this recipient

Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.

Awards with the same topic code

Verified by an exact topic code match. This is not a text-similarity match.

Research funding history

21 SBIR/STTR records share this UEI (2001–2025). Reported award amounts total $15,251,994. Reported amounts are not federal obligations.

Phases: Phase I, Phase II

Agencies: Department of Health and Human Services, Department of Defense, Department of Agriculture

Agency intelligence

Department of Defense

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