Photochemical ClO2 Decontaminant for Biological Agent Neutralization

DHS requires the ability to respond to an attack with biological agents. Specifically, it requires a decontaminant to kill anthrax spores on building exteriors and interiors, and even large outdoor areas. In this proposal we describe an innovative bio-agent decon technology that is particularly suitable for decon over wide areas; and as far as we are aware, no other technology in development can be used on such a large scale. Prior to the Phase I effort, this proposed technology had already demonstrated efficacy against chemical warfare agent simulants and anthrax surrogates. During the Phase I effort the technology was improved, and tests with bacterial spores demonstrated the ability to achieve an 8-log reduction within 15 minutes. The technology demonstrated excellent performance on glass, plastic, painted wallboard and soil. In this proposed Phase II DHS project, we further develop the technology to produce an optimized formulation to combat anthrax in the field. TDA will acquire the data and information required to support EPA registration of a disinfectant product with claims of efficacy against anthrax.