SBIR/STTR Research Award
Genetically Programmable Spherical Nucleic Acids as Rapidly Adaptable Nanotherapeutics
Award amount
$986,621Program and phase
SBIR · Phase IIAward year
2013Award details
- Awarding agency
- Department of Defense
- Branch
- Defense Advanced Research Projects Agency
- Recipient company
- Exicure, Inc.
- Proposal award date
- 2013-08-01
- Contract end date
- 2015-07-31
- UEI
- DHJTJ8VK9KC9
- Solicitation number
- 2012.1
- Topic code
- SB121-003
Research abstract
AuraSense Therapeutics is developing oligonucleotide-modified gold nanoparticles called Spherical Nucleic Acid (SNA) constructs, which are a powerful new way of regulating cellular gene expression. AuraSense Therapeutics will use SNAs as genetically programmable antimicrobial agents in a manner to provide a rapid and effective way to develop next-generation antibacterial agents. The outcome of this work will be a new approach to generating bactericides: a genetically programmable rapidly adaptable nanoparticle therapeutic (RANT). The strategy is designed to be rapidly re-programmed to counter microbial threats, both natural and engineered.
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- Topically-delivered Mutation-specific Gene Targeting for Epidermolytic Ichthyosis
- Topically-delivered Targeted Gene Suppression of Immune Activation in Psoriasis
- Genetically Programmable Spherical Nucleic Acids as Rapidly Adaptable Nanotherapeutics
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- PNA-Based Rapidly Adaptable Anti-Microbial Nanoparticles
- Rapidly Adaptable Nanotherapeutics
- PNA-Based Rapidly Adaptable Anti-Microbial Nanoparticles
- Rapidly Adaptable Nanotherapeutics
Research funding history
4 SBIR/STTR records share this UEI (2012–2014). Reported award amounts total $1,510,792. Reported amounts are not federal obligations.
Phases: Phase I, Phase II
Agencies: Department of Health and Human Services, Department of Defense