Augmented Reality Head Mounted Display for Magnetic Resonance Imaging Guided Inte

DESCRIPTION provided by applicant The broad long term objective is to develop a low cost easy to use system that can convert diagnostic MRI scanner into a functional neurosurgical MRI suite The specific aims of the project are Develop the display only mode of the HMD that integrates MRI realtime scans and device tracking annotation into a stereoscopic D display Feasibility of such HMD has been demonstrated in Phase I of the project Develop a hybrid image based and gradient tracking based head positioning system for the augmented reality system to provide head position in the MRI coordinate system at the edge area of the scanner Develop the augmented reality mode of the HMD that presents D anatomic data from previously acquired MRI onto neurosurgical operation field at the edge of the scanner Develop application specific MRI protocols that provide non distorted high resolution D rendered images with multiple contrast characteristics e g T T FLAIR MP RAGE etc and the planning and visualization software interface to incorporate these images to procedure planning and guidance using augmented reality Conduct phantom tests to demonstrate adequate operation of the HMD in its two modes of operation Conduct animal tests to evaluate the HMD in conducting percutaneous interventions and open neurosurgical procedures The proposed project complies with two of the four specific goals of PA namely The development and optimization of fully integrated cancer imaging monitoring and therapy systems Partnerships among small business and academic clinical centers in order to reach the research goals The development of the technology and the eventual product for clinical use will be done jointly by Robin Medical Inc a small business specializes in the development of navigation systems for MRI and the Magnetic Resonance Research Center MRRC at the University of Maryland Baltimore having extensive experience in human and large animal research in MRI and development of customized scan sequences Robin Medical will develop a head mounted display HMD and head mounted augmented reality system HMARS based on feasibility demonstration in Phase I The HMD will provide a D display of realtime or previously acquired MR images along with realtime tracking annotation The HMARS will provide an augmented reality display composed of view of the surgical field obtained by head mounted cameras MR images and tracking annotation The MRRC group will develop customized MRI sequences for real time guidance and display of D rendered structures and will conduct the technical and animal experimentation with the system PUBLIC HEALTH RELEVANCE The proposed project will enable better resection of tumors hemorrhagic clots and other brain lesions with less damage to healthy brain tissue and critical brain structures The effect on patients and society is enormous patients will have longer survival and less impairment in their functional capacity following the surgical treatment The society will benefit from a reduced hospitalization following the procedure and in the long term reduced need for physical rehabilitation to patients less disability payments all translating to reduced healthcare cost to manage patients with brain tumors