SBIR/STTR Research Award
Design Automation Software for Biomimetic Surface Presentation with DNA Origami
Award amount
$150,000Program and phase
SBIR · Phase IAward year
2012Award details
- Awarding agency
- Department of Defense
- Branch
- Office for Chemical and Biological Defense
- Recipient company
- PARABON NANOLABS, INC.
- Proposal award date
- 2012-12-06
- Contract end date
- 2013-12-14
- UEI
- MXWGP7E3TFM8
- Solicitation number
- 2012.2
- Topic code
- CBD12-103
Research abstract
A development program is proposed for a design automation software package that enables the generation of complex surfaces, with user defined or automated definition of point charge and hydrophobic/hydrophilic properties, using DNA origami as a presentation substrate. Building upon existing software for DNA origami design, this project will result in software able to optimize DNA staples and other origami modifications to achieve target charge and hydration force distributions. The objects to be generated with this software will be able to mimic any of the many surface/surface interactions found in biological or technological applications. Such design software will significantly expand the capabilities of users to produce systems that are capable of highly specific interactions with target macromolecular species.
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- A System for Engineering Nanocarriers Able to Transport Cargo Across the Blood-Brain Barrier
- Kin-X: A Software System for Rapid and Distant Kinship Inference and Automated Pedigree Reconstruction
- A nanoengineering platform for programmable gene editing therapies against rare diseases
- A System for Engineering Nanocarriers Able to Transport Cargo Across the Blood-Brain Barrier
- Novel whole-genome analysis methods for Alzheimer's risk prediction
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- Design Automation Software for Biomimetic Surface Presentation with DNA Origami
- Software for Design and Validation of DNA Nanostructure Surface Patterning
Research funding history
38 SBIR/STTR records share this UEI (2010–2025). Reported award amounts total $23,614,568. Reported amounts are not federal obligations.
Phases: Phase II, Phase I
Agencies: Department of Defense, Department of Health and Human Services, National Science Foundation, Department of Homeland Security