Next Generation Integrated Electrophoretic Nanofluidic Biochip Sensor Platform for the THz Spectroscopic Finger Printing of Biological Species and Age

Redondo Optics Inc. (ROI), proposes to develop and demonstrate a next generation integrated electrophoretic nanofluidic biochip (INTRay-Nanochip) sensor platform for the"label-less"THz spectroscopy finger printing of biological species and agents. In the proposed Phase II of this program, ROI will focus on the engineering development of a manufacturable optical nanolithography technology to enable the cost affordable production of disposable fully integrated electrophoretic nanofluidic biochip arrays, and to use the develop nanofluidic biochips for the extensive THz testing and assessment of the INTRay-Nanochip effectiveness for the THz fingerprinting detection, identification, and classification of biological materials and/or bio-agent targets. Nanotechnology is emerging as the critical field for the next generation evolution of analytical biochip technology that will provide significant breakthroughs for affecting biomedicine. At the completion of the Phase II program, ROI will have develop a manufacturable cost affordable nanolithography production of disposable INTRay-Nanochip arrays for the accurate label-less THz spectroscopy detection and identification of biological species such as DNA, RNA, proteins, and enzymes to enable the detection and identification of biological species. The range of commercial applications for the INTRay-Nanochip technology is very broad covering fields as different as pharmaceutical development, food testing, clinical diagnostics, forensics, environmental analysis, and biodefense.