SBIR/STTR Research Award
Flexible Ion-Mediated Artificial Retina
Award amount
$190,499Program and phase
STTR · Phase IAward year
2014Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- LAMBDAVISION INCORPORATED
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- SJTNSW7KD295
- Solicitation number
- PA13-235
- Topic code
- NEI
Research abstract
DESCRIPTION (provided by applicant): A flexible, protein-based, ion-mediated retinal implant is proposed for the restoration of vision for patients with retinal degenerative diseases, such as age-related macular degeneration (AMD) and retinitis pigmentosa(RP). The implant under development uses the retinal- containing protein, bacteriorhodopsin (BR), to convert light into a pH gradient. This gradient is capable of activating the neural circuitry of the retina, specificall the bipolar and ganglion cells. Bacteriorhodopsin is a light-driven proton pump isolated from a salt-marsh archaeon and this protein has a quantum efficiency nearly identical to rhodopsin, the protein in the rod outer segments of the eye. The high thermal and photochemical stability of BRmake it an excellent candidate for use as the photoactive medium in a protein-based retinal implant. The implant will operate by using a local pH gradient to activate the neural circuitry of the retina by decreasing the pH in the milieu surrounding th
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- On-Orbit Solution Recycling Methods to Improve Scale of Layer-by-Layer Artificial Retina Manufacturing
- On-Orbit Solution Recycling Methods to Improve Scale of Layer-by-Layer Artificial Retina Manufacturing
- Feasibility study for an automated Machine Learning analytics platform for better process control of artificial retina in-space manufacturing
- Implementation of a Layer-by-Layer Manufacturing Apparatus for the Assembly of Protein-Based Retinal Implants in Low Earth Orbit
- Optimization of the Manufacturing Parameters for the Assembly of Protein-Based Retinal Implants in Microgravity
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- Humidifeye Plug for Dry Eye Disease
- A Novel Therapeutic to Promote Corneal Repair
- Drug Screening Platform in the Light-Responsive Human Eye
- RetiVue EntireEye - A Handheld, High-Resolution, Non-Contact, One Image, Widefield Retinal Screening Camera for Premature and Healthy Newborn Babies
- The iD2: A Smart Eye Drop Cap Monitor for Eye Drop Adherence
Research funding history
8 SBIR/STTR records share this UEI (2014–2024). Reported award amounts total $3,160,201. Reported amounts are not federal obligations.
Phases: Phase I, Phase II
Agencies: National Aeronautics and Space Administration, National Science Foundation, Department of Health and Human Services