SBIR/STTR Research Award
Rapid Magnetomotive Thrombolysis for Stroke
Award amount
$218,751Program and phase
SBIR · Phase IAward year
2014Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- Pulse Therapeutics, Inc.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- RL7DEN9VENV1
- Solicitation number
- PA14-071
- Topic code
- NINDS
Research abstract
DESCRIPTION (provided by applicant): Acute ischemic stroke (AIS) is the result of a blood clot in a cerebral artery. It remains a leading killer and the leading cause of long-term disabilit, annually impacting over 700,000 Americans [10]. Because brain tissue rapidly dies, time to reperfusion is critical in both preventing death and improving neurological outcomes. While current annual costs related to ischemic stroke are high in the United States (US), they are projected to increase from 72B in 2013 to 183B by 2030 [14]. Intravenous (IV) administration of tissue plasminogen activator (tPA) remains the standard of care for AIS [15], despite a small ~10% chance for a full recovery and a gt65% chance of death or severe disability [16]. While tPA has been proven to offer statistically-significant benefits, albeit low, in AIS [11] [12] [13], the dose- dependent bleeding associated with tPA has resulted in a low ~8% administration rate in the US. As a result, a large majority of stroke victims are greatly u
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- Magnetically Enhanced Diffusion for Intra-Arterial Treatment of Acute Ischemic Stroke
- Magnetic Targeting and Dose Reduction of Tenecteplase in the Treatment of STEMI for Underserved Populations
- Magnetically Enhanced Diffusion for Intra-Arterial Treatment of Acute Ischemic Stroke
- Rapid Magnetomotive Thrombolysis for Stroke
- Rapid STEMI Fibrinolysis for Underserved Populations
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- Enhancing Healthcare Delivery and Patient Outcomes: Noninvasive Wireless Sensors to Improve Ventricular Shunt Monitoring, Reduce Imaging, and Alleviate the Burden on Providers, Patients, and Families
- Commercialization Readiness Pilot for Flow Acceleration for Stroke Thrombolysis (FAST) System
- 3D in vitro model of genetic and sporadic FTD: accelerating novel therapeutic development
- Tacrolimus-eluting nerve guidance conduit for enhanced regeneration in critical-sized peripheral nerve injuries
- Promoting tissue repair and functional recovery after spinal cord injury by targeting the microtubule regulatory protein Fidgetin-like 2: Supplement for Imaging System
Research funding history
6 SBIR/STTR records share this UEI (2014–2021). Reported award amounts total $4,854,288. Reported amounts are not federal obligations.
Phases: Phase I, Phase II
Agencies: Department of Health and Human Services