SBIR/STTR Research Award
Novel APCI source
Award amount
$164,916Program and phase
SBIR · Phase IAward year
2014Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- MASSTECH, INC.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- V1GZWNZE4F65
- Solicitation number
- PA13-234
- Topic code
- NIGMS
Research abstract
DESCRIPTION (provided by applicant): Significant increase in the efficiency and speed of atmospheric pressure chemical ionization (APCI) in tandem mass spectrometry (MS/MS) will have a profound impact on its applications to the entire analytical field of characterization of drugs, metabolites, lipids, steroids, etc. A broad applicability of APCI-based MS analysis makes it a unique analytical tool specifically targeting trace amounts of many chemical and biological substances. We plan to build a novel APCI ion source based on atmospheric dielectric barrier discharge (DBD) to significantly improve efficiency and specificity of ACPI-MS based detection method. PUBLIC HEALTH RELEVANCE PUBLIC HEALTH RELEVANCE: Atmospheric pressure ionization is a broadly used technique in the analysis of complex chemical and biological samples providing reliable identification of drugs, disease-specific metabolites, steroids, antibiotics, etc. utilizing mass-spectrometers. We plan to develop a novel APCI source that
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- New Subatmospheric MALDI MS Imaging Platform
- Lossless interface for ultrasensitive MS-based proteomics of single cells
- New Ionization Technique for MS Imaging
- Development of new approaches to FTICR mass spectrometry
- Microfluidic-based device for ambient mass analysis
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- Three-Dimensional Spatio-Temporal Control of Lipid Nanoparticle Manufacturing for Improved Nucleic Acid Delivery
- Paradigm-changing, versatile, scalable and cost-effective technology for monthly injections of peptide drugs
- Project MATCH: Multi-spectral AI/ML powered Burn and Wound Evaluation Technology using a Cost-Effective Handheld Device.
- A versatile platform to isolate cells from three-dimensional samples after spatial and temporal profiling
- Development of an Educational Product for Accelerating Solutions for Commercialization and Entrepreneurial Development (ASCEND) in Western IDeA States
Research funding history
22 SBIR/STTR records share this UEI (2010–2017). Reported award amounts total $5,417,920. Reported amounts are not federal obligations.
Phases: Phase I, Phase II
Agencies: Department of Health and Human Services, National Aeronautics and Space Administration, National Science Foundation, Department of Defense, Department of Commerce, Department of Energy