SBIR/STTR Research Award
TOPIC 366: I-PARTS INTEGRATED PLATFORM FOR ANTI-CANCER RADIATION THERAPEUTICS SCREENING
Award amount
$1,964,216Program and phase
SBIR · Phase IIAward year
2019Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- PACT & HEALTH LLC
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- PYHDD9LBJ8B4
- Solicitation number
- Not reported
- Topic code
- NCI
Research abstract
Tumor Irradiation during cancer treatment induces clonogenic death that can be best assessed by colony forming assaysThese colony forming assays are laborious and never utilized in high throughput screeningHTSformatsWe propose to develop anintegrated platform for HTS clonogenic survival assayfor cancer drug screening as well as radiation effect modulation screeningNamedI PARTSIntegrated platform for anti cancer radiation therapeutics screening combines the recent technological advances in cell culture automationmicrofluidicsand high speed image analysis along with NIST traceable dosimetry based HTS X ray irradiationThe I PARTS adopts modular multimodal microscopy to capture the real time colony growth with phase contrastluminescencefluorescence or physical features through tomographyCommerciallythe product has the scope and feasibility to analyze various cancer drugs with variable X ray dosesand simultaneously in different cell linesFutherthis novel single cell array clonogenic platforms will allow improved plating efficiency in clonogenic assay systemsExperimental validation and commercialization will be pursued during this proposalI PARTSan integrated instrument is designed and developed to discover new cancer drugs required for combined cancer therapyThis instrument and the technology is miniaturized such that cancer drugs and radiation treatment can be tailored for individual patientsthe ongoing goal of personalized medicine
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- TOPIC 394 - A VERSATILE RADIATION-TRIGGERED PHOSPHOR PLATFORM FOR LOCALIZED ANTI-CANCER THERAPY
- I PARTS INTEGRATED PLATFORM FOR ANTI CANCER RADIATION THERAPEUTICS SCREENING
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- Mini-reflectance confocal microscope (Mini-RCM) for aiding skin cancer diagnosis and treatment
- Development of small molecule therapeutics targeting AR-V7 for prostate cancer
- Decentralized Clinical Trial of Effectiveness of EnergyPoints App to Guide Acupressure Use for Fatigue and Sleep Disturbances in Cancer Survivors
- Optimized targeted radiotherapy of pancreatic cancer
- Adaptive imaging for pioneering multiplexed spatial profiling of tumors and tissues for cancer research and diagnosis
Research funding history
3 SBIR/STTR records share this UEI (2017–2019). Reported award amounts total $2,562,837. Reported amounts are not federal obligations.
Phases: Phase I, Phase II
Agencies: Department of Health and Human Services