SBIR/STTR Research Award
Advanced Bactericidal Urinary Catheters Based on Electromodulated Nitric Oxide Release
Award amount
$199,908Program and phase
SBIR · Phase IAward year
2014Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- BIOCREDE INC.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- K718SE8C5CY5
- Solicitation number
- PA13-050
- Topic code
- NIDDK
Research abstract
DESCRIPTION (provided by applicant): We propose a completely new, low cost and robust bactericidal urinary 100% silicone Foley catheter with a gt3-6 month shelf-life, that will utilize electromodulated delivery of nitric oxide (NO) for up to 45-60 d to serve as a potent antimicrobial/antibiofilm agent. The first generation device will possess a stable inorganic nitrit salt reservoir within on lumen, in which the nitrite can be converted electrochemically (at surface of microwire) to NO via a simple Cu(II)-ligand redox mediator. The NO released quickly diffuses out of the silicone walls onto the urine collection lumen and the catheter's outer surface to prevent/disrupt biofilm formation that will eliminate catheter-associated urinary tract infections (CAUTI). The special, ISO13485 compliant, 20Fr triple-lumen 100% silicone Foley catheter has been manufactured via an OEM company, and its unique third lumen will be employed by Biocrede Inc to contain and seal off the NO releasing formulation that is electro
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- Bactericidal Intravascular Biosensor for Continuous Reading of Lactate in the lCU Ph2
- Bactericidal Intravascular Biosensor for Continuous Reading of Lactate in the ICU
- Advanced Nitric Oxide Release Bactericidal Urinary Catheters
- Reduction of Tunneled Dialysis Catheter Dysfunction Via Long Term Nitric Oxide Re
- Advanced Nitric Oxide Release Bactericidal Urinary Catheters
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- ND Enabling Studies for CMT-101, a Novel Gene Therapy for Glycogen Storage Disease 1b
- Wearable Metabolic Sensor for Monitoring of Lactate and Glucose for People with Diabetes
- Novel Over-the-Scope Platform for Control of Variceal Bleeding
- Tolerogenic Nanotherapy to Delay Type I Diabetes
- An intravascular Bioartificial Pancreas (iBAP)
Research funding history
6 SBIR/STTR records share this UEI (2013–2018). Reported award amounts total $3,547,593. Reported amounts are not federal obligations.
Phases: Phase I, Phase II
Agencies: Department of Health and Human Services