Development of a high-density wireless ECoG device for neuroscience research

DESCRIPTION (provided by applicant): Title Development of a high-density wireless ECoG device for neuroscience research Project Summary In this Small Business Innovation Research (SBIR) proposal, Cortera Neurotechnologies aims to develop a microsystem forlong-term neural activity recording in animal models of neurological disease. Existing neural recording devices require wires for powering and communication, and use penetrating electrode arrays that cause scarring and limit recording longevity to a few months. Our device will record electrocorticographic (ECoG) signals from non-penetrating electrodes placed on the surface of the cortex and relay them wirelessly to an external reader. Today, ECoG arrays are used clinically to localize the seizure focus before epilepsy surgery. Recently, researchers have become increasingly interested in ECoG recordings for neuroscience research since it allows access to recordings from human brains. Commercial ECoG grids enable recordings with spatial resolutions of 2-4