SBIR/STTR Research Award
Bioactive Calcium Phosphate Glasses for Hyperthermia
Award amount
$50,000Program and phase
SBIR · Phase IAward year
1993Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- Not reported
- Recipient company
- MO-SCI Corp.
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- MJFMGBBB6EJ7
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
A new family of bioactive iron calcium phosphate glasses will be evaluated as thermoseeds for hyperthermia of cancers, especially bone tumors. Through appropriate heat treatment and atmosphere control, the Fe3+/Fe2+ ratio can be adjusted to achieve the desired magnetic hysteresis. The heat generating characteristics of these glasses under external magnetic induction will be studied as a function of glass composition, processing, sample geometry and microstructure. One or more candidate glass compositions will be identified for use in Phase II study where such material will be used in various in vitro, in vivo evaluations. Glass composition formulation takes into account of magnetic properties, bioactivity and glass forming characteristics. An appropriate balance among these properties will make such glass ideal as filler to bone defects after curettage of bone tumors, as filler in bone cements, and at the same time it is used as thermoseeds. In addition, iron calcium phosphate glasses can be made resorbable.
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- Compliant Glass Composite Sealants for SOFC Stacks
- Development of Iron Phosphate Waste Forms for Fission Products Waste Streams
- Development of Hermetic Sealing Glasses for Solid Oxide Fuel Cells
- Development of Cost-Effective YSZ Coating Methods for SOFC Interconnects
- Development of Iron Phosphate Wasteforms for Fission Products Waste Streams
Research funding history
33 SBIR/STTR records share this UEI (1988–2018). Reported award amounts total $6,181,304. Reported amounts are not federal obligations.
Phases: Phase I, Phase II
Agencies: Department of Defense, Department of Energy, National Science Foundation, Department of Health and Human Services, Environmental Protection Agency, National Aeronautics and Space Administration