SBIR/STTR Research Award
Pharmaceutical-scale Synthesis of Oligonucleotides
Award amount
$742,146Program and phase
SBIR · Phase IIAward year
1995Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- Not reported
- Recipient company
- Biosearch Technologies, Inc
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- NX7NLJUNSEU6
- Solicitation number
- Not reported
- Topic code
- Not reported
Research abstract
The projected use of oligonucleotides and their analogs as antisense and antigene therapeuticagents has created a need for efficient methods for their synthesis. Currently available system usingbatch, vortex, or column reactors are inherently incapable of efficient operation at the preparative scaledesired (100 millimole or larger). This grant will develop of novel synthesis reactor architecture coupledwith a new highly economical solid support to provide a practical means for the preparation of ODN'sat the 100g to 1 KG scale. The instrumental design will allow the execution of all available chemistriesat the highest possible efficiency.
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- Development and Commercialization of Analyte Specific Reagents (ASRs) for the Diagnosis of Rickettsial Diseases on FDA-cleared Real-time PCR Platforms
- Development and Commercialization of Analyte Specific Reagents (ASRs) for the Diagnosis of Selected Arthropod-Borne Viruses on FDA-Cleared Real-time P
- Development of a Simple and Rapid Assay for Field Detection of Dengue Viral RNA
- Development and Commercialization of Analyte Specific Reagents (ASRs) for the Diagnosis of Rickettsial Diseases on FDA-cleared Real-time PCR Platforms
- Development and Commercialization of Analyte Specific Reagents (ASRs) for the Diagnosis of Selected Arthropod-Borne Viruses on FDA-Cleared Real-time P
Research funding history
24 SBIR/STTR records share this UEI (1987–2010). Reported award amounts total $6,757,218. Reported amounts are not federal obligations.
Phases: Phase I, Phase II
Agencies: Department of Health and Human Services, Department of Defense