SBIR/STTR Research Award

High-Sensitivity Benzene Detector for Environmental Field Surveys

Award identifier 3f7a322ab38eb896c13eb13fab1cad08c6a396efcc69d5b154a17ffdf6fe34c7Awarding agency Department of Health and Human Services · National Institutes of Health

Award amount

$294,253

Program and phase

SBIR · Phase I

Award year

2024

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Award details

Awarding agency
Department of Health and Human Services
Branch
National Institutes of Health
Recipient company
PHYSICAL SCIENCES INC.
Proposal award date
2024-06-04
Contract end date
2025-05-31
UEI
RMG1AZ1ZH8Q7
Solicitation number
PA23-230
Topic code
R

Research abstract

Project Summary/Abstract Benzene is a known carcinogen linked to leukemia with primary entry into the human body via the lungs, thus detecting, tracking and localizing emission sources in real-time are critical for preventing personal exposures. Premature death from air pollution (due to household air, ambient particulates and ozone) has increased drastically over the past two decades and was responsible for over 6.7 million deaths in 2019. The complexity and high operational cost of existing laborious measurement tools for benzene are responsible for infrequent air sampling activities. The lack of a real-time continuously monitoring benzene instrument for ambient air is making the impact of environmental exposures on the general population very difficult to assess. An easily-operating instrument capable of measuring benzene continuously in real-time with sensitivity of parts-per-billion by volume (ppbv) and adaptable to typical survey modalities (e.g. mobile, fixed, and walking) is the overall goal of this research and development program. The proposed project will improve both scientific knowledge on the impact of benzene on the health of the general population and technical capability in the measurement of benzene in real-time with high-sensitivity and fast time response. The Phase I Specific Aims are to engineer a laboratory prototype to detect benzene, establish the performance of the laboratory prototype, and demonstrate operations in outdoor urban environments. This proposed benzene detector will take advantage of key enabling technologies including recently available room-temperature quantum cascade lasers, custom compact system electronics designs, rugged multipass measurement cell designs, and data analytics for estimating emission rate and source. This real-time continuously monitoring benzene detector will enhance the understanding of its impact on human to reduce or eliminate cancers caused by exposure to benzene.

Technology keywords

Not reported

Other awards by this recipient

Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.

Research funding history

1,763 SBIR/STTR records share this UEI (1983–2026). Reported award amounts total $698,949,224. Reported amounts are not federal obligations.

Phases: Phase I, Phase II, Phase II – Direct to Phase II

Agencies: Department of Defense, National Aeronautics and Space Administration, Department of Health and Human Services, Department of Energy, National Science Foundation, Environmental Protection Agency

Agency intelligence

Department of Health and Human Services

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