SBIR/STTR Research Award
Novel Self-closing 12F Mitral Valve Repair System to Percutaneously Treat Moderate to Severe Regurgitation Using Transcatheter Edge-to-Edge Repair (TEER) Technique Via Femoral Vein Access.
Award amount
$494,825Program and phase
SBIR · Phase IIAward year
2024Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- MEDFREE INC
- Proposal award date
- 2024-04-01
- Contract end date
- 2026-03-31
- UEI
- R4V7MLYWDUN5
- Solicitation number
- PAR23-219
- Topic code
- NHLBI
Research abstract
Project Summary The MEDFREE® Valve Repair System will innovatively improve upon the current market leading MitraClip device, while leveraging and building on the proven Transcatheter Edge-to-Edge Repair technique. We aim to address this vastly unmet percutaneous structural heart market by delivering a simpler, easier-to-use device in a smaller 12F catheter system that can be used by a single operator. MEDFREE has already completed preclinical GLP studies in porcine model (Cohort A: n=2, 30 days; Cohort B: n=5, 140 days) with outstanding results. MRI and Durability (fatigue) studies were also completed with outstanding results. We are now seeking funds via NIH Commercialization Readiness Program, in preparation for EFS/FIH clinical studies.
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- SBIR Phase I: Novel Self-Closing, Transcatheter, Edge-to-Edge Repair Device to Percutaneously Treat Tricuspid Valve Regurgitation Using Jugular or Femoral Vein Access
- Mitral Valve Repair System to Percutaneously Treat Moderate to Severe Regurgitation Using Alfieri Edge-to-Edge Technique
- Mitral Valve Repair System to Percutaneously Treat Moderate to Severe Regurgitation Using Alfieri Edge-to-Edge Technique
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- DUCTUS ARTERIOSUS STENT TO IMPROVE CONGENITAL HEART DEFECT MORTALITY
- Head Up CPR and Aortic Occlusion to Improve Survival after Refractory Cardiac Arrest
- Free-Breathing Dynamic Cardiopulmonary Function Imaging System to use with Xenon MRI
- The Next Wave of Asthma Therapeutics
- Bearingless flux reversal motor for neonatal and pediatric extracorporeal life support applications
Research funding history
4 SBIR/STTR records share this UEI (2020–2024). Reported award amounts total $3,107,825. Reported amounts are not federal obligations.
Phases: Phase II, Phase I
Agencies: Department of Health and Human Services, National Science Foundation