Low-cost Diagnostic Platform for Aquaculture

EmergingDx Inc. in collaboration with Michigan State University will leverage on-goingprograms and their collective expertise to develop a rapid low-cost multiplexed colorimetricquantitative loop-mediated isothermal amplification (qLAMP) microfluidic based diagnostic devicewith high sensitivity and selectivity for screening reproductive fluids/gametes to be used forbreaking the vertical transmission of pathogens in aquaculture.In Phase I period we will develop and demonstrate a paradigm shift concept for detection of fishpathogens. EmergingDx's proposed colorimetric microfluidic based diagnostic device involves (i)adapting MSU's existing LAMP assay capable of identifying Flavobacterium psychrophilum inovarian fluid and milt (ii) a self-contained robust rapid low-cost low power hand-held novelmicrofluidic device and (iii) colorimetric detection and data analytics with a phone app forquantification and data storage/transmission. At the end of the Phase I program we will deliver 1) adetailed feasibility study to demonstrate the scientific technical and commercial merit of ourdiagnostic platform; and 2) a technology transition plan.