SBIR/STTR Research Award

Super-resolution dual-energy dental CT based on distributed x-ray source and photon counting detector

Award identifier 5cb609556b5a6399b50305c14e7b3b51161428f2bcd1b5b5b20f3e54c72b27e9Awarding agency Department of Health and Human Services · National Institutes of Health

Award amount

$221,668

Program and phase

STTR · Phase I

Award year

2021

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Award details

Awarding agency
Department of Health and Human Services
Branch
National Institutes of Health
Recipient company
TETRAIMAGING LLC
Proposal award date
2021-09-21
Contract end date
2022-09-21
UEI
HFW2MYZMLMP6
Solicitation number
PA19-021
Topic code
NIDCR

Research abstract

ABSTRACT With cone-beam CTandapos;s introduction in dentistry, dental clinicians could not only have profound knowledge of oral pathology but could also enhance the access to a detailed view of the underlying structures and their relations. Dental CBCT could be justified for presurgical diagnosis, preoperative planning and preoperative transfer for oral implant rehabilitation. The image quality of CBCT, however, is suboptimal and suffers from strong image artifacts stemming from excessive x-ray scattering, limited detector performance. Spatial resolution, the most important parameter objectively defining image quality, is insufficient for many dental applications where the fine details often have to be depicted. We will develop and validate a novel dental imaging system that not only fundamentally eliminates the image quality problems and but also can produce superior image resolution in 3D images. The super-resolution dual-energy Tetrahedron Beam CT (TBCT) employs a novel multi-pixel thermionic emission x-ray (MPTEX) source with wobbling focal spots as well as an energy-resolved photon-counting detector (PCD). TBCT scans the patient with a stack of fan beams that have a very low scatter-to-primary ratio (SPR); The PCD detector can count x-ray photons without electronics noises, thus can reduce radiation exposure and dental artifacts due to photon starvation; The dual-energy capacity of PCD further eliminates beam-hardening artifacts and supports material decomposition; The flying focal spots and Time-delay-integration (TDI) detection will compensate gantry motion, and super-resolution 3D images can be reconstructed with optics-model based iterative image reconstruction (IIR). Super-resolution dental TBCT will fit in the gap of high-performance 3D imaging in dentistry, allow further advancing the productivity and quality of care in dental practice. The following specific aims have been designed to accomplish this goal: Aim 1: Develop MPTEX source with variable focal spot size and location; Aim 2: To develop and validate a super-resolution dental TBCT benchtop imaging system.NARRATIVE Cone-beam computed tomography (CBCT) technology provides three-dimensional image viewing, supports advanced procedures into the clinical workflow, but its image quality, especially spatial resolution, is insufficient for many applications. To address the deficiency of dental CT, we will develop a novel super- resolution tetrahedron beam CT (TBCT) with dual-energy capacity based on a distributed x-ray source with wobbling focus spots and time-delay-integration (TDI) photon-counting detector (PCD). It will overcome the problems of the current dental CBCT systems and produce superior image quality with unpreceded image resolution.

Technology keywords

Not reported

Other awards by this recipient

Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.

Awards with the same topic code

Verified by an exact topic code match. This is not a text-similarity match.

Research funding history

6 SBIR/STTR records share this UEI (2011–2024). Reported award amounts total $5,010,400. Reported amounts are not federal obligations.

Phases: Phase I, Phase II

Agencies: Department of Health and Human Services

Agency intelligence

Department of Health and Human Services

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