SBIR/STTR Research Award

Development of Human Monoclonal Antibody Therapeutic against Klebsiella pneumoniae Infection

Award identifier 52056893623e0fd6563fd02f273a809f1d54c380dc27eaab157c37f27077628aAwarding agency Department of Defense · Defense Health Agency

Award amount

$249,563

Program and phase

SBIR · Phase I

Award year

2021

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Award details

Awarding agency
Department of Defense
Branch
Defense Health Agency
Recipient company
Technology Holding, LLC
Proposal award date
2021-02-10
Contract end date
2021-09-09
UEI
U52NGYKN42H6
Solicitation number
20.2
Topic code
DHA202-003

Research abstract

Antibiotic resistant infections are a principal concern for the Department of Defense and society at large due to the current lack of available treatments. Monoclonal antibodies represent a promising drug class that could be applied to antibiotic resistant infections to harness a patients own immune system to effectively combat the invading threat. In this program we present an optimized workflow to yield high affinity monoclonal antibody candidates against surface antigens from common infectious disease which is increasingly antibiotic resistant.

Technology keywords

Not reported

Other awards by this recipient

Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.

Awards with the same topic code

Verified by an exact topic code match. This is not a text-similarity match.

Research funding history

138 SBIR/STTR records share this UEI (1983–2025). Reported award amounts total $44,688,257. Reported amounts are not federal obligations.

Phases: Phase I, Phase II, Phase II – Direct to Phase II

Agencies: Department of Defense, Department of Energy, National Science Foundation, National Aeronautics and Space Administration, Environmental Protection Agency, Department of Agriculture

Agency intelligence

Department of Defense

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