SBIR/STTR Research Awards

GAAS/A1GAAS HETEROSTRUCTURE POINT-CONTACT CONCENTRATOR CELLS

Kopin Corporation · National Aeronautics and Space Administration

Phase I1987$50,000

N/A

GENERALIZED ANALYTICAL TECHNIQUES FOR THE METABALOME

IONWERKS INC · Department of Health and Human Services

Phase II2005$99,994

Glioma Therapeutics Targeting Glioma Pathogenesis-related Protein

L2 DIAGNOSTICS LLC · Department of Health and Human Services

Phase I2008$219,461

DESCRIPTION (provided by applicant): Gliomas are malignant tumors that arise from glial cells in the central nervous system and are among the deadliest of human cancers. These tumors are notorious for their aggressive a…

GEROTEST: A WEB SITE ASSESSMENT TOOL

GEROTECH CORPORATION · Department of Health and Human Services

Phase I2002$99,618

DESCRIPTION (provided by applicant): Adults over age 60 constitute the fastest growing market of Internet users; a common reason for being online is to access health information. However, most web sites are not designed…

Gigabit/Second Random Number Generator Using White Noise Generated by Delayed Optical Homodyne

STRUCTURED MATERIALS INDUSTRIES, INC. · Department of Commerce

Phase I2006$75,000

As more and more information is stored digitally and transmitted over the Internet, data and communication security becomes an ever more severe problem facing the military, the government and the financial industry, bot…

GaN Semi-Insulating Substrates

Ocis Technology LLC · Department of Defense

Phase I2002$69,997

Nitride based semiconductors offer a wide range of electronic and optical properties that will permit greatly improved performance of electronic, photonic and optoelectronic devices and circuits. GaN-based LEDs are now…

Genetic Selection to Clone Chondrogenic Regulators

VACCINEX, INC. · Department of Health and Human Services

Phase I2001$99,999

DESCRIPTION (Provided by Applicant): Our ability to develop drugs to effectively treat musculoskeletal diseases like osteoarthritis is limited by the absence of drug targets (genes) central to the etiology of these dise…

Genetic Designs for High-Efficiency Macrolide Production

FERMALOGIC, INC. · Department of Health and Human Services

Phase II1995$749,941

The macrolides are microbial natural products with many uses in clinical and veterinary medicine. Erythromycin is the best studied example of a macrolide antibiotic; rapamycin and FK506 are promising new immunosuppressa…

GENE THERAPY DEVICE FOR TREATMENT OF HEMOPHILIA B

NEPHROS THERAPEUTICS, INC. · Department of Health and Human Services

Phase I1998$100,000

N/A

Genetic Arrays for Antibiotic Target Identification

ELITRA PHARMACEUTICALS, INC. · Department of Health and Human Services

Phase I2003$109,379

DESCRIPTION (provided by applicant): Discovery and development of new antibiotics is widely recognized as an urgent medical need. However, despite intensive R&D efforts at several major pharmaceutical companies, few pro…

Gamma Secretase Assays to Discover Drugs for Alzheimer's

AMERICAN LIFE SCIENCE PHARMACEUTICALS, INC. · Department of Health and Human Services

Phase II2005$1,541,520

DESCRIPTION (provided by applicant): Alzheimer's disease (AD) is a long-term, debilitating disorder that causes loss of memory and cognitive functions. There is an urgent need for effective therapeutic agents to amelior…

Growth, Evaluation And Modeling Of High Tc Superconducting Multilayer Structures

Excel Superconductors, Inc. · Department of Defense

Phase I1993$50,000

Residual stress in thin-film materials resulting from thermal and chemical strains is a continuing problem in the synthesis of superconducting thin films. The probelm exists not only in the superconducting layers, but a…

GAAS VERTICAL SUPERLATTICES FOR MONOLITHICALLY INTEGRATABLE LWIR DETECTOR ARRAYS

Spire Corporation · Department of Defense

Phase I1991$49,936

ONE PROMISING APPROACH TO THE FABRICATION OF LONG-WAVELENGTH INFRARED (LWIR) DETECTORS IS THE USE OF GAAG-A1GAAS MULTIPLE-QUANTUM-WELL (MQW) STRUCTURES, ALTHOUGH A MAJOR DIFFICULTY IS CAUSED BY THE FACT THAT, TO BE DETE…

Gelled LH2/UFAL/LOX Propellant System

Orbital Technologies Corporation · National Aeronautics and Space Administration

Phase II2002$599,999

ORBITEC proposes to use ultra-fine aluminum powder (UFAL) to develop a gelled LH2 fuel and LOX propellant system. This innovation will increase the performance and density of LH2/LOX and the combustion efficiency of LH2…

Goal-directed decision support system for treating perioperative fluid deficits

Arcos, Inc. · Department of Health and Human Services

Phase I2014$225,022

DESCRIPTION (provided by applicant): Goal-directed decision support system for treating perioperative fluid deficits Gastro-intestinal, cardiac and orthopedic surgeries can result in significant blood and fluid losses.…

GENETIC ANALYSIS OF CORONARY ARTERY DISEASE

MOLECULAR TOOL, INC. · Department of Health and Human Services

Phase II1998$421,551

N/A

Generating HIV resistant cells from conditionally transformed HSC cell lines

Taiga Biotechnologies, Inc. · Department of Health and Human Services

Phase I2008$161,192

DESCRIPTION (provided by applicant): Using a method of retroviral gene transduction we have been able to generate conditionally immortalized long-term hematopoietic stem cell lines from primary mouse bone marrow stem ce…

GROWTH OF ND:LAF<V>3<D> CRYSTALS FOR DIODE LASER PUMPING

Crystal Systems, Inc. · National Science Foundation

Phase I1989$42,073

IT IS NECESSARY TO EVALUATE NEW LASER MATERIALS WITH INCREASED WALL PLUG EFFICIENCY. CURRENTLY SEMICONDUCTOR LASER ARRAYS HOLD THE POTENTIAL TO BE EFFECTIVE OPTICAL PUMPING SOURCES. IN ORDER TO UTILIZE THE SEMICONDUCTOR…

Growth of Large Diameter Silicon Carbide Boules

BANDGAP TECHNOLOGIES, INC. · Department of Defense

Phase II2003$750,000

Absence of low defect density large diameter (~100 mm) silicon carbide (SiC) wafers is a major barrier for the commercial production of SiC-based devices. Hence, the development of a process to produce large diameter bu…

Gene Expression Assays of Natural and Mutant Type I IFN

LIFETIME PHARMACEUTICAL, INC. · Department of Health and Human Services

Phase I2004$100,000

DESCRIPTION (provided by applicant): Microarray analysis, in combination with new statistical tools, is a powerful technology for studying gene expression. Dr. He has successfully applied this approach in his lab to ana…

GROWTH FACTOR GENE THERAPY FOR WOUND HEALING

SELECTIVE GENETICS, INC. · Department of Health and Human Services

Phase I1999$100,000

Not Available With the high cost and limited flexibility of testing weapon systems in an actual operational (flight, etc.) environment, there are many cost and technical benefits to be obtained by conducting preliminary…

GENETICALLY IDENTICAL WHHL RODENTS

Transgenic Sciences Inc. · Department of Health and Human Services

Phase II1991$467,762

THE WATANABE HERITABLE HYPERLIPIDEMIC (WHHL) RABBIT IS AN EXCELLENT MODEL FOR FAMILIAL HYPERCHOLESTEROLEMIA, A COMMON HUMAN GENETIC DISEASE. THE HIGH COST, LIMITED SUPPLY, AND GENETIC VARIABILITY HAVE RESTRICTED THE POT…

Gas Imaging and Monitoring Camera

AMETHYST RESEARCH INC · Department of Energy

Phase I2016$224,997

Significant improvements in the technology to monitor greenhouse gases are required. In particular there is need to be able to simultaneously monitor both small (~m) and large area sites (~ 100km) and in rugged/inaccess…

GROUND TRUTH PHYTOPLANKTON SENSOR

CIENCIA INC · National Aeronautics and Space Administration

Phase II1997$599,958

N/A

Good Natured Food Campus - An Economic and Cultural Engine for the NorthSide Regeneration Plan

RAINBOW ORGANIC FARMS CO · Department of Agriculture

Phase I2014$97,068

A vastly under-served community, located in an impoverished, 1,500-acre tract in the city of St. Louis, Missouri, is in dire need of increased accessibility to nutritious food. Most of the buildings are torn down, decay…