SBIR/STTR Research Award

Compact Targeted Brain Cooling System

Award identifier 585ea3a14ff3228aa244db8819c7ad76cade9b336d5f20a736dfa570fc5b7a0aAwarding agency Department of Defense · Defense Health Agency

Award amount

$149,961

Program and phase

SBIR · Phase I

Award year

2016

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Award details

Awarding agency
Department of Defense
Branch
Defense Health Agency
Recipient company
MAINSTREAM ENGINEERING CORP
Proposal award date
2016-09-21
Contract end date
2017-04-20
UEI
YR8FJBGXWRR1
Solicitation number
2016.1
Topic code
DHP16-008

Research abstract

Traumatic brain injury (TBI) impacts over two million Americans annually, and is the signature injury of the Iraq and Afghanistan conflicts. Therapeutic hypothermia is a promising neuroprotective technique for treating TBI, but reduced body temperature is a threat to soldiers in military operations with multiple injuries. Mainstream has proposed a novel vapor compression cooling system that overcomes the key limitations of existing systems and provides selective brain cooling without impacting body temperature. This will provide TBI treatment without the accompanying negative side effects associated with reduced whole body temperature in a compact, portable system that can be applied at the point of injury and during transport.

Technology keywords

Not reported

Other awards by this recipient

Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.

Awards with the same topic code

Verified by an exact topic code match. This is not a text-similarity match.

Research funding history

518 SBIR/STTR records share this UEI (1987–2025). Reported award amounts total $184,860,329. Reported amounts are not federal obligations.

Phases: Phase I, Phase II, Phase II – Direct to Phase II

Agencies: Department of Defense, Department of Energy, National Aeronautics and Space Administration, Department of Transportation, Department of Health and Human Services, Environmental Protection Agency

Agency intelligence

Department of Defense

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