SBIR/STTR Research Award
Enabling Metabolic Imaging Using Feedback Driven Magnetic Resonance Spectroscopy
Award amount
$213,347Program and phase
SBIR · Phase IAward year
2014Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- MILLIKELVIN TECHNOLOGIES, LLC
- Proposal award date
- Not reported
- Contract end date
- Not reported
- UEI
- NDANTBWE8SH5
- Solicitation number
- PA14-071
- Topic code
- NIBIB
Research abstract
DESCRIPTION (provided by applicant): Elevated levels of glycolysis are known to correlate with the presence and disease stage of various cancers. This phenomenon, known as the Warburg effect, provides the biological basis of Fluoro-Deoxyglucose Positron Emission Tomography (FDG PET) studies. FDG is taken up by the cell in a manner similar to glucose but then remains trapped in the cell for times exceeding an hour. If the 19F atom in the FDG molecule has been irradiated to 18F it can then detected and spatially located using the tomography device. Radioactive 18FDG PET has been shown to be able to spatially locate tumors on length scales down to approximately 8 mm in clinically available devices and has been widely used in the detection and staging of tumorsfor more than 30 years. However, it imposes a non-trivial radioactive burden on the patient; for this reason, 18FDG FDG PET scans for humans are typically limited to not more than once per 12 months per patient and only after a tissue diagnosis has al
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- Driven Feedback Enhanced Magnetic Resonance Spectroscopic Quantification of Non-Radioactive 19 FDG in Tumors
- A Novel Method For Producing 15N Enriched NH3 For Manufacture of U15N Accident Tolerant Fuel
- Improved Imaging of an MR Molecular Agent Using Driven Feedback Contrast Enhancement
- Manufacture and Supply of Hyperpolarized Chloroform for Use as an NMR Solvent
- Enabling Metabolic Imaging Using Hyperpolarized 13C Magnetic Resonance
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- Deep-UV Microscopy for Real-Time Adequacy Analysis of Bone Marrow Aspirates
- Deep learning image classification model for pediatric ear disease
- Development of a Multispectral Kerrison Rongeur for Dura and Nerve Root Detection
- Non Invasive Urine Output Monitor
- SoundScape: A portable small animal imager to accelerate drug development
Research funding history
6 SBIR/STTR records share this UEI (2009–2020). Reported award amounts total $1,303,402. Reported amounts are not federal obligations.
Phases: Phase I
Agencies: Department of Health and Human Services, Department of Energy