AI-Enabled Ultra-Miniature Earpiece for Sleep Microarousal Detection and Cognitive Performance Prediction

This project proposes to enhance the STAT Lumia device by developing and validating the algorithm developed on phase I for detecting sleep microarousals, a key factor in assessing sleep quality and predicting cognitive performance. The Lumia, an innovative in-ear wearable, provides continuous physiological monitoring, offering significant potential for real-time sleep analysis and cognitive readiness assessment.The study will be conducted in two phases. Phase I involves recruiting 30 participants for an overnight polysomnography (PSG) sleep study, during which both standard clinical PSG data, and Lumia data will be collected. The primary focus will be on training and validating the microarousal detection algorithm, with an emphasis on accuracy across diverse sleep conditions.In Phase II, the project will evaluate the ability of the STAT device to predict next-day cognitive performance based on detected microarousals. After the overnight recordings, participants will complete a cognitive test in the lab to assess cognitive readiness. The study will analyze whether various sleep metrics derived from Lumia—such as the number of arousals, Arousal Index, total sleep time, sleep efficiency, heart rate spikes, and HRV crashes—can effectively predict next-day cognitive performance.Further, the project will refine the hardware based on feedback from human subject testing, ensuring optimal signal quality, usability, and wearability. The final phase will involve comprehensive testing to validate the device’s readiness for deployment in military and clinical settings.The project will conclude with the delivery of four fully optimized Lumia Developer Kits to the Defense Health Agency (DHA), accompanied by a detailed final report. This report will summarize Phase II outcomes, including performance metrics, algorithm accuracy, and recommendations for future research or deployment. The successful completion of this work will position the STAT Lumia device as a vital tool for real-time physiological monitoring and cognitive performance prediction, with broad applications in military operations and healthcare.