SBIR/STTR Research Award
Spatial Genomics for in situ single cell expression analysis in the brain
Award amount
$1,989,076Program and phase
SBIR · Phase IIAward year
2020Award details
- Awarding agency
- Department of Health and Human Services
- Branch
- National Institutes of Health
- Recipient company
- SPATIAL GENOMICS, INC.
- Proposal award date
- 2020-09-04
- Contract end date
- 2022-08-31
- UEI
- C2CPGG8RZLV9
- Solicitation number
- PA19-272
- Topic code
- 101
Research abstract
SUMMARY
Spatial Genomics, Inc. is commercializing seqFISH technology that can visualize thousands of
genes at the mRNA level in single cells with spatial information preserved. Recent advances now
make it possible to achieve 10,000 gene multiplexing in single cells directly in tissues (Eng et al.,
Nature 2019). With this technology, novel cell types can be discovered in situ and spatial
organizations can be directly identified and visualized in brain tissue sections.NARRATIVE
Spatial Genomics is developing a transformative technology to profile the transcriptome in single
cells in situ. This technology can image gene expression directly in the brain and has many
applications to neurodegenerative diseases.
Technology keywords
Not reported
Other awards by this recipient
Verified by the same UEI. These are other public SBIR/STTR award pages, not a merged company record.
- Next generation spatial genomics tools for the human brain
- Spatial single cell analysis of the human Alzheimer's Disease brain
- Spatial genomics analysis of tumor samples
- Multi-modal spatial genomics in the mouse and human brains
- Spatial and single cell analysis of tumor microenvironment by seqFISH+
Awards with the same topic code
Verified by an exact topic code match. This is not a text-similarity match.
- High bandwidth all-optical electrophysiology
- Fast multicolor confocal fluorescence imager for neural network mapping
- Advanced culture and recording system for long-term electrophysiological profiling in human brain organoids
- Commercialization Readiness for a Portable PET Insert System for Simultaneous TOF-PET and MR Brain Imaging
- Design and Development of an Advanced Functional MRI Software as Medical Device (SaMD) forClinical Trials and Therapeutic Applications in Neuropsychiatry
Research funding history
7 SBIR/STTR records share this UEI (2018–2025). Reported award amounts total $13,546,078. Reported amounts are not federal obligations.
Phases: Phase II, Phase I, Phase II – Direct to Phase II
Agencies: Department of Health and Human Services