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SBIR/STTR Research Awards
Explore federally funded small business innovation research, technology awards, participating companies, and agency investments.
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Tissue and Airway Evaluation for Emphysema Intervention
VIDA DIAGNOSTICS, INC. · Department of Health and Human Services
Phase II2006$749,892
DESCRIPTION (provided by applicant): VIDA Diagnostics is taking a leading role in pioneering new image display and analysis tools which take advantage of the rapid advancements in multi-row detector computer tomography…
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THE PHOTOCHEMICAL GENERATION OF PLANAR WAVEGUIDES IN SOL-GEL GLASSES
Physical Optics Corporation · National Science Foundation
Phase II1997$285,214
THE COMMERCIAL REALIZATION OF THE PROMISE OF INTEGRATED OPTICS TECHNOLOGY DEPENDS ON THE ESTABLISHMENT OF A COST-EFFECTIVE, RELIABLE METHOD OF FABRICATING ACTIVE AND PASSIVE WAVEGUIDING STRUCTURES IN A THIN FILM FORMAT.…
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THE LONG TERM OBJECTIVE IS TO PRODUCE AN INEXPENSIVE, EASY TO USE, PORTABLE READOUT DEVICE FOR EXISTING FIBER OPTIC SENSORS OR "OPTRODES".
Ord Inc. · Department of Energy
Phase I1986$49,974
THE LONG TERM OBJECTIVE IS TO PRODUCE AN INEXPENSIVE, EASY TO USE, PORTABLE READOUT DEVICE FOR EXISTING FIBER OPTIC SENSORS OR "OPTRODES". THE READOUT INSTRUMENT, IN CONJUNCTION WITH THE OPTRODES WILL BE USED TO DETECT…
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TAS::75 0893::TAS RAPID QUANTITATIVE POINT OF CARE TEST FOR NICOTINE METABOLITE RATIO, SILOAM BIOSCIENCES, INC. CINCINNATI, OH
SILOAM BIOSCIENCES · Department of Health and Human Services
Phase II2011$997,254
Recent clinical research has established that this ratio is indicative of the activity of the CYP2A6 enzyme that metabolises nicotine. Nicotine is metabolized to COT and then to 3HC. People with high activity of this en…
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TOPIC 418 ""HIGH THROUGHPUT SPATIALOMICS PROFILING FOR THICK TUMOR TISSUES""
Arvetas Biosciences, Inc. · Department of Health and Human Services
Phase I2021$400,000
A critical barrier to constructing molecular and cellular tumor atlases is the lack of spatialomics tools that can rapidly and cost-effectively profile multi-omics in large and thick tumor tissues with molecular resolut…
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THERMAL CONDUCTIVITY, DIFFUSIVITY PROBE DEVELOPMENT
Vatell Corporation · National Science Foundation
Phase I1990$50,000
N/A
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Targeting c-Myc and Akt with PP2A reactivation therapy for the treatment of breas
ONCOTIDE PHARMACEUTICALS, INC. · Department of Health and Human Services
Phase I2013$300,000
DESCRIPTION (provided by applicant): Each year in the United States over 270,000 women will be diagnosed with breast cancer and over 40,000 will die from the disease. While multiple forms of breast cancer exist, a commo…
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THE OBJECTIVE OF THIS PROJECT IS TO DEVELOP A DEDICATED CLINICAL SYSTEM FOR TESTING AND ANALYZING OCULAR MOTILITY.
Neuro Logic Systems · Department of Health and Human Services
Phase I1984$42,810
THE OBJECTIVE OF THIS PROJECT IS TO DEVELOP A DEDICATED CLINICAL SYSTEM FOR TESTING AND ANALYZING OCULAR MOTILITY. COMMERCIALLY, OUR GOAL IS TO PRODUCE A LOW-COST, USER-FRIENDLY HARDWARE/SOFTWARE PACKAGE SPECIFICALLY DE…
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Theoretical Modeling of High Heat Flux Heat P
Boyd Lancaster, Inc. · National Science Foundation
Phase I2000$99,978
N/A
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THE SCIENCE OF ADDICTION FOR DEAF HIGH SCHOOL STUDENTS
SOCIAL SCIENCES INNOVATIONS CORPORATION · Department of Health and Human Services
Phase I2005$99,961
N/A
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TAS::75 0849::TAS OPTION PERIOD II, YEAR 2, SBIR TOPIC 255 DEVELOPMENT OF A TRIPTOLIDE DERIVATIVE AS A THERAPEUTIC AGENT
MYELORX LLC · Department of Health and Human Services
Phase I2011$740,277
Acute Myeloid Leukemia (AML) is an aggressive hematopoietic cancer originating in the bone marrow. AML is the most common form of adult leukemia; older adults have a 6-8% best current therapy response rate. The long-ter…
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Tissue and Airway Evaluation for Emphysema Interventions
VIDA DIAGNOSTICS, INC. · Department of Health and Human Services
Phase I2004$100,000
DESCRIPTION (provided by applicant): The widespread deployment of high-speed multi-detector CT (MDCT) scanners in the US market is creating opportunities for 3D analysis as single breath hold scans with isotropic voxels…
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THEORETICAL AND EXPERIMENTAL CHARACTERIZATION OF FIBER-MATRIX INTERFACE IN SIC REINFORCED GLASS CERAMICS
ADTECH SYSTEMS RESEARCH INC · Department of Defense
Phase I1989$49,978
ALTHOUGH THE USE OF CERAMIC COMPOSITES IN AEROSPACE SYSTEMS IS MONOTONICALLY INCREASING, THERE ARE NOT MANY ANALYTICAL AND EXPERIMENTAL STUDIES REVEALING THE UNIQUE CHARACTERISTICS THESE MATERIALS CAN PROVIDE. IT IS BEL…
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THOUSAND-OBJECT TRACKING WITH NEURAL NETS
Memistor Corp. · Department of Defense
Phase II1990$476,000
NEW COMPUTATIONAL MEANS NEED TO BE DEVELOPED FOR THE PRACTICAL SOLUTION OF REAL-TIME TRACKING OF A THOUSAND OR MORE SPACE-BORNE OBJECTS AT ONE TIME. IT IS ASSUMED THAT, DURING AN ENGAGEMENT, DATA WOULD ARRIVE FROM A NUM…
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Throughput-Enhanced Multi-Wavelength Guidedwave Optical Interconnects for High-Density Holographic Memory
RADIANT RESEARCH, INC. · Department of Defense
Phase I1998$99,999
New developments in the three-dimensional memory devices have created demand for high-speed and large-volume data handling interconnects between memory devices and processing elements. Electrical interconnects fail to k…
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THE OBJECT OF THIS PROJECT IS TO PRODUCE A KIT THAT UTILIZES ANTI-CSAP MONOCLONAL ANTIBODIES (MABS) FOR CLINICAL RADIOIMMUNODETECTION (RAID) OF COLORECTAL AND PANCREATIC CANCERS.
IMMUNOMEDICS, INC. · Department of Health and Human Services
Phase I1985$50,000
THE OBJECT OF THIS PROJECT IS TO PRODUCE A KIT THAT UTILIZES ANTI-CSAP MONOCLONAL ANTIBODIES (MABS) FOR CLINICAL RADIOIMMUNODETECTION (RAID) OF COLORECTAL AND PANCREATIC CANCERS. PHASE I WILL BE DEVOTED TO SELECTION OF…
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THE DISPLAY AND ANALYSIS OF VARIABLE RESOLUTION SPATIAL DATAIN A GIS ENVIRONMENT
Delta Data Systems, Inc. · National Aeronautics and Space Administration
Phase I1991$49,563
N/A
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THE NAVAL AIR SYSTEMS COMMAND (NAVAIR) NEEDS A METHODOLOGY TO PROVIDE A MEANS OF IDENTIFYING, EVALUATING, AND PRIORITIZING THOSE TECHNOLOGIES WHICH BEST MEET FUTURE NAVY OPERATIONAL NEEDS IN AREAS OF NAVAIR INTEREST.
B-k Dynamics Inc · Department of Defense
Phase I1983$49,909
THE NAVAL AIR SYSTEMS COMMAND (NAVAIR) NEEDS A METHODOLOGY TO PROVIDE A MEANS OF IDENTIFYING, EVALUATING, AND PRIORITIZING THOSE TECHNOLOGIES WHICH BEST MEET FUTURE NAVY OPERATIONAL NEEDS IN AREAS OF NAVAIR INTEREST. TO…
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Targeting surface-bound IgE as a novel allergy therapeutic
Sixal Inc · Department of Health and Human Services
Phase I2012$400,000
DESCRIPTION (provided by applicant): The overall goal of this SBIR application is to develop and commercialize a next generation allergy biologic therapy. This novel therapeutic, an anti-IgE monoclonal half antibody, ta…
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THE DEVELOPMENT OF A SMALL-SCALE WATERFALL PAINT STRIPPING SYSTEM
Technical research Associates, Inc. · Department of Defense
Phase I1991$55,000
TECHNICAL RESEARCH ASSOCIATES, INC. AND HILL AIR FORCE BASE PERSONNEL HAVE EXCHANGED IDEAS AND TECHNOLOGIES IN SEVERAL AIR FORCE SBIR PHASE I AND PHASE II PROJECTS. IN THESE PROJECTS, TRA ESTABLISHED SUCCESSFUL POLYURET…
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Towards Simultaneous Single Particle Chemical and Optical Characterization: Development of a Multi-angle Optical Scattering Module for the Aerosol Time-of-Flight Mass Spectrometer
Photon Machines · Department of Energy
Phase I2010$99,940
A large uncertainty in climate models relied on by scientists for understanding of global climate and human impacts is the uncertainty in aerosol particle absorption and scattering. While we know that aerosol scattering…
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TOPIC 428 ""CLOUD-BASED LIQUID-BIOPSY PLATFORM FOR THE CANCER RESEARCH DATA COMMONS
OMICSCRAFT LLC · Department of Health and Human Services
Phase I2021$455,000
Recent advances in cloud-based resources and technologies for multi-omics and imaging analysis have created new opportunities for exploring relationships between histology, molecular events, and clinical outcomes using…
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TARGETABLE BACTERICIDAL PROTEINS TO SPECIFICALLY KILL CLOSTRIDIUM DIFFICILE BACTE
AvidBiotics Corp. · Department of Health and Human Services
Phase I2012$600,000
DESCRIPTION (provided by applicant): The ultimate goal of this proposal and any subsequent phase II proposal is to develop a unique protein agent to prevent Clostridium difficile associated diseases in those patients at…
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TURBINE ENGINE ROTOR SYSTEM FAILURE PREDICTION AND PREVENTION
Systems Control Technology, · Department of Transportation
Phase I1990$49,962
N/A